From the 1880 census, your Margaret (Brindle) Overstreet is living with her son Albert Overstreet in Canton, Missouri.
Name: Margaret Overstreet
Event Type: Census
Event Year: 1880
Event Place: Canton, Lewis, Missouri, United States
Marital Status: Widowed
Race (Original): W
Relationship to Head of Household: Mother
Relationship to Head of Household (Original): Mother
Birth Year (Estimated): 1820
Birthplace: Indiana, United States
Father's Birthplace: Germany
Mother's Birthplace: Germany
Sheet Number and Letter: 43B
Affiliate Name: The U.S. National Archives and Records Administration (NARA)
Affiliate Publication Number: T9
Affiliate Film Number: 0699
GS Film Number: 1254699
Digital Folder Number: 004241900
Image Number: 00091
Citing this Record:
"United States Census, 1880," index and images, <i>FamilySearch</i> (https://familysearch.org/pal:/MM9.1.1/M6XV-MZ9
: accessed 22 Sep 2014), Margaret Overstreet in household of Albert Overstreet, Canton, Lewis, Missouri, United States; citing sheet 43B, NARA microfilm publication T9.
This record states that Margaret's parents were both born in Germany. I would check for Brindle's born in Germany who are living in Indiana in the 1850 census. You will have to be careful of the ages. I saw a Frederick Brindle in Clark County, Indiana who was the right age to be a brother to Margaret.