Nancy was born in 1818. She is enumerated in the 1860 census but not the 1870 census so presumably she died between 1860 and 1870 in Arkansas.
Sources
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MZY8-F6R : 12 April 2016), Elily Wikle in household of Samuel Wikle, Union county, Union, Georgia, United States; citing family 628, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
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DNA Connections
It may be possible to confirm family relationships with Emily by comparing test results with other carriers of her mitochondrial DNA.
Mitochondrial DNA test-takers in the direct maternal line:
Michael Lynn :
AncestryDNA Maternal Lineage (discontinued) Other, haplogroup U, Ancestry member mclynn28
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Emily: