"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M4LD-HLN : 12 April 2016), John Hughs in household of John Hughs, Lauderdale county, Lauderdale, Mississippi, United States; citing family 482, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M4GJ-5FK : 11 August 2016), John M Hughes, Hurricane Creek, Lauderdale, Mississippi, United States; citing enumeration district ED 97, sheet 214C, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d.), roll 0653; FHL microfilm 1,254,653.
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DNA Connections
It may be possible to confirm family relationships with John by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with John: