One of three sisters who never married and lived with or near their brother Fed Nelson.
In 1900 she was living with her nephew Thomas Nelson, son of Fed Nelson.
Sources
1850 US Census: Marshall County, Kentucky
1880 US Census: Sand Spring, Grayson County, Kentucky
1900 US Census: Shrewsbury, Grayson County, Kentucky
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret: