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DNA Connections
It may be possible to confirm family relationships with George by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree:
Sisson-702 and Sisson-14 appear to represent the same person because: they are a clear match on dates, places, and family members. I am following up from a single merge that seems to have uncovered a set of duplicates over several generations.
A father's death date (Sisson-14 died 1607) should not be more than nine months before one of his children's birth dates (Sisson-12 born 1608) .