From Genealogical and Personal History of Western Pennsylvania:
Dr. James Agnew, eldest son of Daniel Agnew, was educated in the college with which his father was connected for so long a term of years, Princeton, and became an exponent of the medical profession. He lived for a time in New Jersey, but later moved to Pittsburgh, Pennsylvania, where he was one of the earliest of physicians. He formed a partnership with Dr. Simpson, and the following advertisement, which appeared in the city directory for the year 1819, shows the wide gulf that separates the professional methods and practices of a century ago from those of our present day : "Drs. Agnew and Simpson have formed a copartnership in the practice of medicine, and cojointly tender their services to their friends and all others who may apply for professional aid. Their shop is at the comer of Third and Wood Streets, where one or both may at all times be consulted." He married the daughter of Governor Howell, of New Jersey, her brother being the father of Mrs. Jefferson Davis, wife of the president of the Confederate States of America, while that league of states stood.
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