Rome on Wikipedia: While Roman mythology dates the founding of Rome at around 753 BC, the site has been inhabited for much longer, making it one of the oldest continuously occupied sites in Europe. It was first called The Eternal City (Latin: Urbs Aeterna; Italian: La Città Eterna) by the Roman poet Tibullus in the 1st century BC, and the expression was also taken up by Ovid, Virgil, and Livy. Rome is also called the "Caput Mundi" (Capital of the World). After the fall of the Western Empire, which marked the beginning of the Middle Ages, Rome slowly fell under the political control of the Papacy, which had settled in the city since the 1st century AD, until in the 8th century it became the capital of the Papal States, which lasted until 1870.
Lazio on Wikipedia: After the Gothic conquest of Italy at the end of the fifth century, modern Lazio became part of the Ostrogothic Kingdom, but after the Gothic War between 535 and 554 and the Byzantine conquest, this region regained its freedom, because the "Roman Duchy" became the property of the Eastern Emperor.