Born at Medina del Campo, he was the son of Ferdinand I of Aragon and Eleanor of Alburquerque. He represented the old line of the counts of Barcelona through the female line, and was on his father's side descended from the House of Trastamara, the reigning House of Castile.
He succeeded as King of Aragon, Sicily, Valencia, Mallorca, & Naples
His married Infanta doña MARÍA de Castilla y León, daughter of ENRIQUE III King of Castile and León & his wife Katherine of Lancaster (Segovia 14 Sep 1401-Valencia 7 Sep 1458) but there were no issue from this marriage.
He had children, but they were not legitimate.
With Margarita Fernandez de Hijar, daughter of Juan Fernandez de Hijar and Timbor de Cabrera
Alfonso V died on 26 June 1458 at Naples, Italy.
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