Hannah married twice. Her three (3) children by her second husband were mentioned in her father's will, but the renown physicist and mathematician Sir Isaac Newton, was conspicuously absent. Newton, however, witnessed will of his maternal uncle, William Ayscough, Rector of Burton Coggles, co. Lincs.
Hannah's first husband Isaac Newton (bur. 06 Oct 1642 Colsterworth, co. Lincs, age 36), was a yeoman. They married in April 1642, but the groom died three months before the birth of their only son, Sir Isaac Newton.
Sir Isaac Newton (b. 25 Dec 1642 [OS] / 04 Jan 1643 [NS] Woolsthorpe, co. Lincs - d. 20 Mar 1726 [OS] / 31 Mar 1727 [NS] London).
On 27 January 1645, Hannah remarried to Barnabas Smith, Rector of North Witham (living 1652; c. abt. Aug 1653 x 1656), at North Witham, co. Lincs. He was a witness of his father-in-law's will.