Isaac Barker was the son of Robert Barker and Lucy Williams.
Isaac Barker was of Duxbury and Marshfield, Massachusetts. and Portsmouth, Rhode Island.
Isaac Barker declared his intentions to marry Judith Prence, daughter of Gov. Thomas Prence and his third wife, Apphia Quick, on December 28, 1665, in Plymouth County, Plymouth Colony. His widow, Judith Prince married second, William Tubbs, of Pembroke in 1691. She died in 1710.
There was a tradition that his wife, Judith Prence, and all her seven sisters were very beautiful.
Children of Issac Barker and Judith Prence were as follow:
Samuel Barker, b. 2 September 1667; died 1 February 1738/9.
Martha Barker, b. about 1680; d. 15 February 1722.
Bathsheba Barker (It is possible that she may have been the Bathsheba Barker who married John Howland in 1718 in Portsmouth, Rhode Island).
The fact that an administrator was appointed for Francis' estate in 1694 (Mar. 26) indicates that he was among the older children; the letter of administration names Samuel as "eldest brother". The daughters were arranged in the order in which they appeared in their grandfather's will. Bathsheba Barker being not named but designated as the youngest.
Isaac Barker was surveyor of Duxbury in 1674 and constable in 1687.
Isaac Barker died on January 31, 1689, in Duxbury, Plymouth County, Plymouth Colony or died on 14 February 1688/9.
↑ 2.02.1 “Barker Pedigree,” by James Atkins Noyes. The New-England Historical and Genealogical Register. [October 1899], Vol. LIII (53). Boston: New-England Historical and Genealogical Society, 1899, p. 427.
Cutter, William R. New England Families, Genealogical and Memorial: A Record of the Achievements of Her People in the Making of Commonwealths and the Founding of a Nation. New York: Lewis Historical Pub. Co, 1915, p. 512. Print.