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Biography
From her father (assuming George is the father)'s will: [1]
Sons; Israel & John, land known as Ephraim Logue tract and land purchased of Richard Oldham;
James & George (land adj Orange Co line known as John Murtree (Murphey) tract;
William& dau., Susannah Barker & Mary Taylor.
Father John Barker:
It looks like there's confusion as to her father was. This is from geni.com:
John Barker (son of Joel Barker and Katherine Harrison) was born Abt. 1720 in Surry Co., VA, and died 1808 in Iredell Co., NC. He married Elizabeth Gilliam on Abt. 1746 in Surry Co., VA, daughter of Hincha Gilliam and Faith Briggs.
Children
+Susannah Barker, b. December 12, 1745, Surry Co., VA, d. Abt. 1812, AL.
Rebecca Barker, b. June 24, 1747, VA.
+Howell Barker, b. February 02, 1748/49, VA, d. September 11, 1847, Iredell Co., NC.
+Mary Barker, b. Abt. 1750, VA.
+Burrell Barker, b. Abt. 1751, VA, d. 1816, Iredell Co., NC.
+Hinchea Barker, b. Abt. 1756, VA, d. Aft. 1840.
+Elizabeth Barker, b. Abt. 1760, VA.
Susannah did outlive her husband so she could have gone to Alabama.
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DNA Connections
It may be possible to confirm family relationships with Susannah by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Susannah: