Topham Beauclerk was born on 22 December 1739, the only son of Lord Sidney Beauclerk and his wife, Mary Norris, and a great-grandson of King Charles II. He was christened on 19 January 1740 in St James', Westminster. 
He attended Oxford University (Trinity College).
He died in 1780 at his home in Great Russell Street, Bloomsbury.
↑ Baptismal record St James, Westminster (19 January 1739 (OS?) Topham Beauclerk born 22 December 1739 son of Sidney Beauclerk and Mary Norris)
James McLaverty, ‘Beauclerk, Topham (1739–1780)’, Oxford Dictionary of National Biography, Oxford University Press, 2004; online edn, May 2006 accessed 8 June 2017. This is a subscription site but access is free of charge to readers of British libraries whose library subscribes.
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It may be possible to confirm family relationships with Topham by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: