Charles Best
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Charles Herbert Best (1899 - 1978)

Charles Herbert Best
Born in West Pembroke, Maine, USAmap
Ancestors ancestors
Husband of — married 3 Sep 1924 in Toronto, Ontario, Canadamap
Died in Toronto, Ontario, Canadamap
Profile last modified | Created 21 Jan 2018
This page has been accessed 427 times.
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Charles H. Best was born in West Pembroke, Maine on February 27, 1899 to Luella Fisher and Herbert Huestis Best, [1]Canadians from Nova Scotia.

Charles Best and Frederick Banting
As a 22-year-old medical student at the University of Toronto, Best worked as an assistant to the surgeon Dr. Frederick Banting and contributed to the discovery of the pancreatic hormone insulin, which led to an effective treatment for diabetes. After receiving his doctor of science degree from the University of London in 1928, he was appointed head of U of T's department of physiological hygiene. The following year he became professor and chairman of the department of physiology.

After Banting's death, Best was appointed his successor as director of the University of Toronto's department of medical research. In 1953 the university opened the Charles H. Best Institute.

He married Margaret Hooper Mahon in Toronto in 1924[2] and they had two sons. One son, Dr. Henry Best, was a well-regarded historian who later became president of Laurentian University in Sudbury, Ontario. Best's other son was Charles Alexander Best, a Canadian politician and geneticist.

He died on March 31, 1978 in Toronto, Ontario, just six days after the sudden death of his son Charles. Best is interred in Mount Pleasant Cemetery, Toronto (section 29) not far from Sir Frederick Banting.


  1. "Maine Vital Records, 1670-1921," database with images, FamilySearch ( : 28 September 2017), Charles H Best, 27 Feb 1899; citing Pembroke, , Maine, United States, Division of Vital Statistics, State Board of Health, Augusta; FHL microfilm.
  2. "Ontario Marriages, 1869-1927," database with images, FamilySearch ( : 11 March 2018), Charles Herbert Best and Margaret Hooper Mahon, 03 Sep 1924; citing registration , Toronto, York, Ontario, Canada, Archives of Ontario, Toronto; FHL microfilm 1,838,048.

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Charles is 17 degrees from Cecil B. DeMille, 25 degrees from Rosalie Neve and 17 degrees from Henry VIII of England on our single family tree. Login to find your connection.

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Categories: Ontario, Medical Figures