There is a long sketch called "Genealogical Sketch and History of the Bissonette Family"[1] that recollects the marriage of Joseph and Eunice. I have his wife as Agnes, but the sketch does say that Eunice Roberts Bissonette was the sister of Polly Roberts Knaggs, who is indeed Agnes's sister. Could it be as simple that her name is Eunice, not Agnes?
Rev Christian Denissen, Genealogy of the French Families of the Detroit River Region (GFFDRR), 1987, Detroit Society for Genealogical Research, page 119 #5.
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DNA Connections
It may be possible to confirm family relationships with Joseph by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Joseph: