Isabell was born in 1746. She was the daughter of John Blair. She passed away in 1831.
Sources
FamilySearch (Mormon church's family tree database) record # LY88-PLM
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DNA Connections
It may be possible to confirm family relationships with Isabell by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isabell: