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DNA Connections
It may be possible to confirm family relationships with Samuel by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Samuel:
Samuel Brister, 1814, married Serena Guess in Hesterville, Miss. They had 7 children, William Hockaday, Edward, Mahala, Isaiah, Jane, John, and Saphronia. His Father was Thompson Brister, mother was Nancy Hockaday Brister. John Terrel was not mentioned in my source, but there was a possibility of other children. Source family records, and Ancestry.com.