From a newspaper clipping found in her sister's Bible:
Another marriage. Who now? Why Mr. John Shepherd and Miss Sarah Brizendine. On last Thursday the 8th inst., the handsome couple drove to the home of Dr. Horn and dismounted from their neat buggy, tied up their steeds, and marched in. The NOT [sic] was soon tied and the cheerful party were made happy as man and wife the remainder of life. Only a few attendants accompanied the bride and groom to their rural home, among whom we mention the right gallant Mr. Finley, Miss Hammon and Miss Mary Alley, the accomplished school marm. Mr. Finley behaved with becoming dignity as he drove off, with cigar in mouth, reins in hand, and sweet-heat [sic] on either side.
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M6X8-6H5 : 7 September 2017), Sarah A Brizendine in entry for Emma Brizendine, 1880; citing enumeration district ED 32, sheet 167D, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d), roll 0694; FHL microfilm 1,254,694.
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It may be possible to confirm family relationships with Sarah by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Sarah: