Elizabeth was born about 1780. She was the daughter of Thomas Brooke and Elizabeth Unknown. Elizabeth was named for mother and was the youngest of five daughters. She married John Simonson. She passed away before 1816.
Sources
Maryland Historical Magazine, Vol. 29, 1934
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DNA Connections
It may be possible to confirm family relationships with Elizabeth by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Elizabeth: