She was known to her sons as "Louie", and this is how she names herself in the family Bible, but the 1880 census lists her as "Lurinda C.", and the 1900 census lists her as "Charlotte" (both times in a parent's household). Son Patrick said that she was partial to her son Ross singing "Charlotte Town".
Louie's maternal grandmother was "Elizabeth Lucinda", but analysis of the 1880 census shows that the enumerator definitely writes an /r/ and not a /c/ (plus there is a "Lucinda" on the page for comparison).
According to her son Patrick, Louie suffered from bad asthma, and this was the eventual cause of her death in the Dillard Hotel Apartments in Hamlin.
Sources
Family Bible. Originally owned by Henry Clay and Louie (Buck) Simonds. Now in possession of their great-grandson C. Simonds. Provides dates of birth and marriage (entered by Louie) and death.
FindaGrave.com. Lurinda Charlotte "Louie" Simons. Photo of headstone on memorial page: http://www.findagrave.com/cgi-bin/fg.cgi?page=gr&GRid=14711177 Son Patrick recalled that his father, Henry, was unhappy that the "Simons" spelling was used for her married name instead of the change he'd made during their married life to "Simonds", but since Henry's family assisted with the burial and headstone, at the time he didn't feel like he could argue. Note that the birth year is one year later than what Louie recorded in her Bible.
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DNA Connections
It may be possible to confirm family relationships with Lurinda by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Lurinda: