Ancestry Family Trees and FamilySearch ancestral and pedigree files commonly contain only tree information and some family history. A few may contain source references, which need to be cited and referenced individually here
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DNA Connections
It may be possible to confirm family relationships with Jesse by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Jesse:
I'm fairly certain that this is identical to the Jesse Cain under Cain-316. I was going through my GEDMatches, and my ancestor shares all the traits of both Jesse Cains. I'm skipping mine, but this should probably be merged with the other to keep with the one profile-one person idea of WikiTree.