Jesse Bartholomew Casey was born in 1726 in Baltimore, Maryland, his father, Abner, was 26 and his mother, Harriet, was 25. He married Phoebe Jane Holloway Casey in 1741 in Baltimore, Maryland. They had 11 children in 12 years. He died in 1790 in Newberry, South Carolina, at the age of 64.
It may be possible to confirm family relationships with Jesse by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: