The great-great-grandparents of First Lady, Laura Bush, James T. Aldridge (1813 - 1884) and Mary Chadwell Aldridge (1815 - 1888), are buried in Porters Cemetery, near the site of Orangeville, Fannin, Texas. Her great-grandparents, Dr. William Franklin Welch and Nancy Jane Aldridge Welch are also buried in Porter's Chapel, although their graves are unmarked today. Their exact burial location is no longer known.
Comparing Kit T824570 (David Douglas) and T379443 (Martha Brown)
(Full Siblings). Match on 51 segments, and all 22 Chromosomes, Largest segment = 153.0 cM, Total of segments > 7 cM = 2,507.4 cM, 51 matching segments. 
"Texas Deaths, 1890-1976," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:K3SR-X7S : accessed 1 May 2016), Chadwell in entry for William E Aldridge, 31 Jan 1936; citing certificate number 2005, State Registrar Office, Austin; FHL microfilm 2,116,782.
"United States Census, 1860," , FamilySearch (https://familysearch.org/ark:/61903/1:1:MXFT-7NM : accessed 13 August 2015), J Aldridge, Beat No 3, Fannin, Texas, United States; from "1860 U.S. Federal Census - Population," database, Fold3.com (http://www.fold3.com : n.d.); citing p. 145, household ID 969, NARA microfilm publication M653 (Washington, D.C.: National Archives and Records Administration, n.d.); FHL microfilm 805,293.
"United States Census, 1870," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MXGT-GCD : accessed 12 September 2015), James Aldridge, Texas, United States; citing p. 57, family 369, NARA microfilm publication M593 (Washington D.C.: National Archives and Records Administration, n.d.); FHL microfilm 553,083.
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/pal:/MM9.1.1/MFN4-CJP : accessed 19 July 2015), Jas Aldridge, Precinct 3, Fannin, Texas, United States; citing enumeration district 25, sheet 380A, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d.), roll 1302; FHL microfilm 1,255,302.
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It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: