Samuel was born in 1816. He was the son of Samuel Clemens. He passed away in 1882.
Sources
Find a Grave, database and images (https://www.findagrave.com/memorial/65337914/samuel-clemens : accessed 25 October 2021), memorial page for Samuel Clemens (16 Feb 1816–22 Nov 1882), Find a Grave Memorial ID 65337914, citing Zoll Cemetery, Fulton County, Illinois, USA ; Maintained by Debra (contributor 47324320) .
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DNA Connections
It may be possible to confirm family relationships with Samuel by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Samuel: