John Compton was born in England and immigrated to the US before the Revolutionary war. 
"...John Compton who bought 200 Acres of land on September 13, 1785 from Lewis and Teresia Duvall for five Shillings..."
Origins of the sons name Lewis Duvall
From a Clan of Compton's:
"Our earliest know Compton ancestor was john Compton who bought 200 acres of land on September 14, 1785 from Lewis and Teresia Duvall for five Shillings. Since the son of this John Compton named his son Lewis Duvall Compton, we wonder if perhaps the wife of john Compton was not a Duvall." What little information that has been peiced together on this Duvall family is that they had one daughter - Elizabeth born in 1769. This family moved to Illinois shortly after the sale of this land. Also this lewis Duvall, b. in 1750 would have been contemporary of John Compton - what if John Compton's sister was Theresa who married Lewis Duvall? Since there is no proof of an Amy, what is the answer? It does seem that there was some sort of connection.
There could have been other children from John, Sr. and Amy Compton:
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↑ Personal papers and notes of Frances T. Gaulden, Clan of Comptons, p. 1-5, Myldred Compton Lankford, Unpublished. Biographical and Historical Memoirs of Southern Arkansas, P. 404 Personal copy in the files of M. Gaulden
↑ Personal papers and notes of Frances T. Gaulden, Clan of Comptons, p. 1, Myldred Compton Lankford, Unpublished. Personal copy in the files of M. Gaulden
Land Deeds,September 13, 1785, Laurens County Clerk of Court.
Descendants of John Compton (abt 1755 - abt 1825) of Laurens County, South Carolina, Charles S Compton, Lincoln, AL : C.S. Compton, [2000?], Birmingham Jefferson Library, Birmingham, AL.
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It may be possible to confirm family relationships with John by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with John: