Frances M. Bryant Guion-Miller Roll Application lists a sister, Nancy, with birth and death dates and no additional information. I've found no other sources that have information about Nancy.
Sources
Guion Miller roll:Frankie Mahaley Bryant Application #18520 NARA M1104 Eastern Cherokee Applications of the U.S. Court of Claims, 1905-1909. Accessed at Fold3 31 January 2015
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DNA Connections
It may be possible to confirm family relationships with Nancy by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Nancy: