Ann Crymes explains, " Her husband, Wirt Barnes, was brother to Nannie Barnes Crymes, wife of Alice's brother, Thomas A Crymes."
Sources
Birth - not found
1850, age 2 - VA, Lunenburg, family 577. "United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:M8D8-CP1 : 23 December 2020), Alice Crymes in household of Janette Crymes, Lunenburg, Lunenburg, Virginia, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).
1860, age 12 - direct link not found. VA, Lunenburg, page 1041, image 705. Roll: M653_1359; FHL Film: 805359.
1870, age 22 - VA, Lunenburg, Pleasant Grove, page 35, family 260. "United States Census, 1870", database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:MFGP-7S7 : 29 May 2021), Alice Crymes in entry for Louisa Crymes, 1870.
1880, age 32 - direct link not found. NC, Halifax, Enfield, ED 316, page 680A. Roll: 966; Family History Film: 1254966.
1900, widowed, age 52 - direct link not found. VA, Roanoke ward 1, ED 91, sheet 15A. Roll: 1739; FHL microfilm: 1241739
1910, age 62 - NC, Guilford, Morehead Twsp, Greensboro ward 1, ED 108, sheet 8A, family 147. "United States Census, 1910," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MLS7-721 : accessed 27 December 2021), Alice M Barnes in household of Wort N Barnes, Friendship, Guilford, North Carolina, United States; citing enumeration district (ED) ED 108, sheet 8A, family 147, NARA microfilm publication T624 (Washington D.C.: National Archives and Records Administration, 1982), roll 1114; FHL microfilm 1,375,127.
1920, age 72 - NC, Guilford, Gilmer Twsp, ED 135, sheet 12B, family 225. "United States Census, 1920", database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:MZNG-CHY : 2 February 2021), Alice M Barnes in entry for W N Barnes, 1920.
1930, age 81 - NC, Guilford, Gilmer Twsp, ED 41-44, sheet 6B, family 70. "United States Census, 1930," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:X33Z-Q5V : accessed 27 December 2021), Alice Barnes in household of W N Barnes, Gilmer, Guilford, North Carolina, United States; citing enumeration district (ED) ED 44, sheet 6B, line 99, family 70, NARA microfilm publication T626 (Washington D.C.: National Archives and Records Administration, 2002), roll 1695; FHL microfilm 2,341,429.
Author: Hazel Savoy Crymes, transcribed by Ellen Crymes Wilkinson 1996 Title: "Treasure Chest of Memories" Publication: Name: Copyrighted 1996, Copies held with Hazel's children and Grandchildren -- not to be published.
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DNA Connections
It may be possible to confirm family relationships with Alice by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Alice: