Estimating date of death. Smith genealogy says only that Frances was Henry's first wife. Children from Henry's second marriage were born in mid-1845 and later.
Sources
The Family of Richard Smith of Smithtown, Long Island: Ten Generations.
Frederick Kinsman Smith, 1967.
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DNA Connections
It may be possible to confirm family relationships with Frances by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Frances: