Findagrave.com reports that Margaret was daughter of John Davis and Elizabeth Whitton and that she was the wife of William M. Self. This resolves previous profile problem in that she was reported as daughter of William Kines, Margaret's mother's first husband.
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Margaret: