The original spelling of the last name may have been Eisele.
May have been, not certain, as notation on Findagrave states.
Married Johanna(h) Sauter in Franklin County, OH, on June 11, 1858.
Per the 1870 census dated 21 Jun 1870, Joseph H. (50), lived with his wife Johanna (33), sons Joseph (11), John (8), and daughter Teresa Eisel (5) in Columbus, Ohio.
Children:
Joseph
John
Theresa
Both the markers for Joseph H., and Jeannette Eisel were most likely made by his son, Joseph J. Eisel, Sr.
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DNA Connections
It may be possible to confirm family relationships with Joseph by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Joseph: