Margaret was born in 1613. She passed away in 1640.
Margaret's maiden name may have been Eliot (Elyot). If she is the Margaret Eliot who married Edward Spalding in Redenhall, England on September 18, 1623 - then our Edward is not the Edward who arrived in Jamestown, VA in 1619 and later moved To Braintree, MA. Instead Edward and Margaret would be the couple who lived, and in Margaret's case, died in Braintree.