Isaac Eaton was the eighth child of the Rev. John and Sarah Stites Gano. He was born near Elizabeth, NJ and died in Frankfort, KY.
Sources
Gano, John. Biographical memoirs of the late Rev. John Gano, of Frankfort (Kentucky), formerly of the city of New York. New York, Printed by Southwick and Hardcastle for J. Tiebout. 1806. *https://archive.org/details/biographicalmemo00gano
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DNA Connections
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isaac: