"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MNW7-6MK : 12 August 2017), Isaac A George, Prairie, Franklin, Arkansas, United States; citing enumeration district ED 64, sheet 835B, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d.), roll 0044; FHL microfilm 1,254,044.
(Alonzo) "United States Census, 1900," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M3HJ-2BB : accessed 27 November 2017), Lon George, Mineral Spring Township, Barry, Missouri, United States; citing enumeration district (ED) 12, sheet 9A, family 188, NARA microfilm publication T623 (Washington, D.C.: National Archives and Records Administration, 1972.); FHL microfilm 1,240,838.
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DNA Connections
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isaac: