Margaret was born about 1821. She passed away in 1899.
From History of Allegheny County, Pennsylvania:
Sources
"United States Census, 1850", database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:M65P-7QQ : Tue Jul 18 00:41:51 UTC 2023), Entry for William W Callings and Margaret B Callings, 1850.
"United States Census, 1880", database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:MCZ1-31G : Thu Aug 03 01:36:41 UTC 2023), Entry for William W. Collins and Margret B. Collins, 1880.
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret: