"United States Census, 1870," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MZ2G-4M5 : 12 April 2016), Isabelle Bartelson in household of Benjamin Bartelson, Pennsylvania, United States; citing p. 4, family 26, NARA microfilm publication M593 (Washington D.C.: National Archives and Records Administration, n.d.); FHL microfilm 552,962.
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MWVL-FWW : 15 July 2017), Isabella Bartilson in household of Ben Bartilson, Hopewell, Washington, Pennsylvania, United States; citing enumeration district ED 251, sheet 276B, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d.), roll 1201; FHL microfilm 1,255,201.
Death certificate for Nancy Isabelle Bartilson, date of death 21-Jan-1921, Pennsylvania, Washington County, Claysville, File number 4956, Registered Number 6, Pennsylvania Historic and Museum Commission; Pennsylvania, USA; Pennsylvania, Death Certificates, 1906-1965; Certificate Number Range: 002501-005500 
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It may be possible to confirm family relationships with Isabelle by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage (beta) of DNA with Isabelle: