Pamela is the grandmother of Samuel L. Clemens (Mark Twain).
After Pamela's husband's death in 1805, she took her five young children to join members of the Goggin family who had settled in Adair County, Kentucky. There, she married Simon Hancock and together they raised the Clemens children to adulthood .
Encyclopedia of American Quaker Genealogy, 1750 - 1930, William Wade Hinshaw, Vol. VI, Page 894, Marriage Bonds of Bedford Co., Virginia, 1797, 10, 23. Samuel [Clemens] & Pamelia Goggin. Samuel Hancock, Surety. Married by John Ayers, Oct. 29, 1797
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It may be possible to confirm family relationships with Pamela by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Pamela: