"Indiana Marriages, 1811-2007," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:27V4-27R : 10 December 2017), Isaac Grisham and Manerva Canada, 04 Jan 1844; citing Washington, Indiana, United States, Marriage Registration, Indiana Commission on Public Records, Indianapolis; FHL microfilm 007030113.
"United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:MHV8-B2C : 19 December 2020), Isaac Grisham, Posey Township, Washington, Indiana, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).
Find a Grave, database and images (https://www.findagrave.com : accessed 17 February 2021), memorial page for Isaac Gresham (1818–1913), Find A Grave: Memorial #185222865, citing Smedley Cemetery, Campbellsburg, Washington County, Indiana, USA ; Maintained by Sharon (contributor 48585755) .
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DNA Connections
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isaac: