James Guthrie was said to have had a great hatred for Indians all of his life due to the impressions made upon him by his mother's tales of suffering at their hands. James was the great-grandfather of Harry C. Guthrie.
Sources
Find a Grave, database and images (accessed 24 August 2021), memorial page for James Guthrie (6 Jan 1786–29 Jun 1851), Find A Grave: Memorial #26917567, citing Shannondale Union Cemetery, Shannondale, Clarion County, Pennsylvania, USA ; Maintained by Al Haxton (contributor 47862792)
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DNA Connections
It may be possible to confirm family relationships with James by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with James: