Martha (Patsey) was born in 1755 at "Pine Slash," Hanover Co., VA, the oldest of six children and three daughters of Patrick Henry and Sarah Shelton. (Her father married a second time and had eleven more children.) She passed away in 1818. 
Her father Patrick Henry had been given 300 acres at "Piney Slash" and six slaves as the dowry for his bride, Sarah, from her father, John Shelton a wealthy landowner and owner of Hanover Tavern.
It is Martha Henry who oversees the care of her ill mother and her five siblings while the family live at Scotchtown.
The letters between Martha Fontaine and her father are very tender and show a special bond between them. It is easy to see how the great patriot came to rely on his oldest child in the care of his ill wife in particular She was also close to Dorothea Dandridge Henry, second wife of Patrick Henry. Martha and Dorothea were both the same age, each born in 1755. Martha Fontaine will name her last child, Dorothea in honor of her stepmother. (bio by: deegraver)
On 2 Oct 1773, when she was eighteen, Martha married John Fontaine (born 1750 at Beaverdam, Virginia, died at “Leatherwood” in 1792 of malaria). Martha, widowed at 37, managed Leatherwood plantation and administered the wills both of her husband and of her brother William.
In the early 1770s Martha meets a local young man, John Fontaine[,] who was born at Beaverdam, Hanover County, Virginia in 1750. His family were French Huguenots who fled France after the St. Barthomew's Day Massacre of 1572. Martha Henry and John Fontaine marry on October 2, 1773 at Scotchtown.
Martha and John Fontaine will live at "Leatherwood" Plantation, a portion of which John Fontaine bought from his father-in-law in 1779.
John Fontaine served as a Captain in the Henry County Militia and fought during the Siege of Yorktown, where he contracted Malaria. He died from the disease in 1792. Martha continued to live at "Leatherwood" for 26 more years. She died at the age of 63 in 1818, and is buried beside her husband.
She died in 1818, at age 63 at Leatherwood, in Henry County, Virginia. Both she and her husband are buried on the plantation.
Sadly, the Leatherwood property will pass from the Fontaine/Henry family; in modern day it will be developed into a shopping mall- the graves of Martha and John Fontaine lie in what was once Leatherwood Plantation, now an asphalt covered parking lot, near Martinsville, Va. Their burial sites are unmarked.
It may be possible to confirm family relationships with Martha by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Martha: