"United States Census, 1820," database with images, FamilySearch  :George Higginson, Henderson, Henderson, Kentucky, United States; citing p. 11, NARA microfilm publication M33, (Washington D.C.: National Archives and Records Administration, n.d.), roll 24; FHL microfilm 186,184.
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It may be possible to confirm family relationships with George by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with George: