Source: S71Vital records of Chelmsford, Massachusetts, to the end of the year 1849. Salem, Mass: The Essex Institute, 1999. Open Library
Source: S77 Title : Chelmsford: Births, Marriages and Death - 1742 transcription Massachusetts, Town and Vital Records, 1620-1988 [Ancestry.com. database on-line]. Provo, UT, USA: Ancestry.com Operations, Inc., 2011. Original data: Town and City Clerks of Massachusetts. Massachusetts Vital and Town Records. Provo, UT: Holbrook Research Institute (Jay and Delene Holbrook).
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Isaac: