She passed away only a few days prior to the census-taker's arrival in 1880.
Sources
Birth and death dates are from Oak Hill Cemetery in Colesburg. Birth place is believed to be Fayette City, Fayette Co., PA, but more proof is needed. Pennsylvania didn't require birth records until late in the nineteenth century.
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DNA Connections
It may be possible to confirm family relationships with Prudence by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Prudence: