The 1891 census shows him with his wife Brenda, and a daughter Hilda.
In 1911, he was living in Ilfracombe, Devonshire.
Research Notes
According to a secondary source (my 2nd cousin Sue), William and Brenda had the following children:
Winifred Holmden, 1866-1932
Hilda Brend Holmden, 1868-1944
Harold Reed Holmden, 1869-1869
Ronald Holmden, 1870-1871
Gerald Holmden, 1872-1958, m. Edith Ellen B. Smith (1875-1929)
Geraldine Holmden, 1872-1959
Sources
"England Births and Christenings, 1538-1975," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:NPWG-FXP : 30 December 2014), William Isbell Batton Holmden, 19 Oct 1835; citing HOW STREET BAPTIST, PLYMOUTH, DEVON, ENGLAND, reference ; FHL microfilm 0590693 (RG4 1215).
"England and Wales Census, 1911," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:XW9P-2YW : 20 January 2015), William Isbell Batton Holmden, Ilfracombe, Ilfracombe, Devonshire, England; from "1911 England and Wales census," database and images, findmypast (http://www.findmypast.com : n.d.); citing PRO RG 14, The National Archives of the UK, Kew, Surrey.
"England and Wales Census, 1891," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:7YKJ-3W2 : 15 October 2015), William J B Holmden, Harborne, Worcestershire, England; from "1891 England, Scotland and Wales census," database and images, findmypast (http://www.findmypast.com : n.d.); citing PRO RG 12, Worcestershire county, subdistrict, The National Archives of the UK, Kew, Surrey.
"England and Wales Death Registration Index 1837-2007," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:QVH7-MWYZ : 4 September 2014), William I B Holmden, 1924; from "England & Wales Deaths, 1837-2006," database, findmypast (http://www.findmypast.com : 2012); citing Death, Barnstaple, Devon, England, General Register Office, Southport, England.
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DNA Connections
It may be possible to confirm family relationships with William by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with William: