Vermont is the birthplace listed in the 1880 census.
Note: I did not include the birthplace listed on the index record below (Canada) as I have found birthplace to be incorrectly indexed in many instances and the original record could not be viewed. NGP June 5, 2017
Sources
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MZFJ-F36 : 14 July 2016), H Otis Wells in household of Elijah Wells, Louisville, St Lawrence, New York, United States; citing enumeration district ED 218, sheet 357B, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d.), roll 0925; FHL microfilm 1,254,925.
"New York Deaths and Burials, 1795-1952," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:FD18-N56 : 29 December 2014), ...is. G. Hosmer in entry for Johanna (Hosmer) Wells, 23 Apr 1891; citing Louisville, St. Lawrence, New York, reference item 1 rn 34; FHL microfilm 1,311,929.
Son's death record names parents: "New York Deaths and Burials, 1795-1952," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:FD18-J45 : 29 December 2014), Joanna Hosmer in entry for Otis H. Wells, 15 Apr 1912; citing Louisville, St. Lawrence, New York, reference item 1 rn 427; FHL microfilm 1,311,929.
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DNA Connections
It may be possible to confirm family relationships with Johanna by comparing test results with other carriers of her mitochondrial DNA.
Mitochondrial DNA test-takers in the direct maternal line: