He was the son of John C. Howell and Essena Elizabeth Osborne. David married first Mary Naomi Edwards (daughter of Thomas Edwards and Mary Brittain) and second, Mary Myriam Ann Edwards (daughter of Ellis Edwards and Ameilia Brittain). He had 12 children altogether.
Sources
Find a Grave, database and images (https://www.findagrave.com/memorial/64204068/david-howell : accessed 13 October 2021), memorial page for David Howell (1 Jul 1796–20 Apr 1866), Find a Grave Memorial ID 64204068, citing Matt Caldwell Cemetery, Jonathan, Haywood County, North Carolina, USA ; Maintained by Lou (contributor 47103297) .
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DNA Connections
It may be possible to confirm family relationships with David by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with David: