Samuel was born in 1764 in Bucks County, Pennsylvania
He was from a Quaker family that lived in Landsdowne, Bucks Co, Pa.
His family moved to Bedford Co., VA about 1770, with his uncles William & Abe.
He married 1st to Sarah Watts, Feb 26, 1784, Bedford co, VA[1]
Child: Hulda, b about 1785 in VA (she married about 1810 in Kanawha Co, WV to Nelson Britt)
So Samuel was probably in Kanawha Co, WV in 1810.
He married 2nd to Elizabeth Wilson, 1821.
Their son, Samuel Jr was born in 1822 in Washington county, Indiana. (He m Margaret Wilson and was a farmer in Illinois)
Samuel probably died in Indiana.
Sources
↑ marriage record:
"Jan. 26, 1784; Samuel Huddleston & Sarah Watts; Wagman Sinclair, Surety; Married by William Johnson, Feb. 26, 1784"
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DNA Connections
It may be possible to confirm family relationships with Samuel by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Samuel: