Gedcoms at Ancestry.com link him to Philip and Rachel (Jackson) Huff, but Granville Hough, Vol. IV, places a different John as son of that couple.
May be the same John Huff who married poss Nancy Cox in 1818, res Fentress Co TN. Ch: John, James, Nancy, Alexander.
Ancestry.com claims a daughter Nancy (1814) married James Crabtree.
Another gedcom at Ancestry.com makes him the man who married Cynthia Sallee, with three children born in the 1850s. His children with Prudence at that site are:
1. Wiley Huff
2. Alexander C Huff b: 1809
3. Preston Huff
4. Didama Huff
5. Nelly Huff
6. Pamelia Huff
7. Matilda Huff
8. John Huff b: 1804 in Virginia
9. Celia Huff b: 1805 in Kentucky
10. Claiborne B. Huff b: 1810
11. Martha Huff b: 1812
John's last name, in the 1850 census, is spelled Hough. Has in his home in 1850 son "Clayborn" and daughter Celia as well as her two sons.
Different list of his children, from Ancestry.com. Children with Prudence Millsap:
1. John HUFF b: 1804 in Virginia
2. Celia HUFF b: 1805 in Kentucky
3. Wiley HUFF
4. Alexander HUFF
5. Claiborne B. HUFF b: 1810
6. Preston HUFF
7. Didama HUFF
8. Martha HUFF b: 1812
9. Nelly HUFF
10. Pamelia HUFF
11. Matilda HUFF
Marriage 2 Cyrene Ann Sallee
1. Brandsford HUFF b: 1851
2. Florence HUFF b: 1855
3. Dian HUFF b: 1859
Bruce York posted this at Ancestry.com, "York's Fentress County Tennessee": Donna Skidmore Barlow -- This is what James Miller Huff's daughter copied. As you can see there were two Prestons. John Huff was her great-grandfather. I am sure James Miller Huff copied it from a Bible.
John Huff Sr. died in 1862
wife Nancy Chisham
Wiley Huff-Never married
Alexander Huff m. Martha Sallee
Clayborn Huff m. Serella Millsaps
Preston Huff (a doctor) m._____Turner
Celia Huff married John Sublett
Didama Huff m. Lewis Huff (Cousin)
Prudy Hufff m. James Mc Gee
Permelia Huff m. Lt. Hiram Marcum
Manerva Huff m. Lt. Cy Claunch
John Huff Sr married #2 Cyrene Ann Sallee Eliott
Son Alexander Huff
Married Martha "Patsy" Sallee
Pamelia Ann Huff 1837-1839
Didama Huff, m. Capt. Martin Van B. Duvall
Nancy Huff m. Lt. Andrew Huff (2nd cousin)
Lt. Preston "Press" Huff m. Brazil Huff (2nd cousin)
Lucinda Huff m. Capt. Eli Hatfield
John Huff m. Sarah Harmon
Mc Cayger Huff m. Matty Washer
Landon Carter Huff m. Juan Sandusky
Mary Clementine Huff m. Marion Francis Crockett then Fleming Williams
James Miller Huff m. Mary E. Brunch
Thursey Jane Huff m. John Moody
Elender Elizabeth Huff m. Millard Filmore Hurst
Alexander C. Huff b. April 10 1858 m. Mary Parmley
Flordia Huff m. Dudley Parmley
User ID: 36D721BABC8646C3BA08DBDF815D48B48946
Date: 13 JUN 2010
Prior to import, this record was last changed 13 JUN 2010.
Text: Chart sent by Granville Hough. This is from Jack Ferguson, Early Times in Clinton County (KY), Vol. 1, pages 124 and 125, "The Huff Family." Granville added notes in his handwriting.
It may be possible to confirm family relationships with John by comparing test results with other
carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share DNA with John: