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Elizabeth was born in 1650. She passed away in 1740.
Oral tradition claims she was the half-breed daughter of "Princess" Nicketti and an unnamed Cavalier (others say her father was a trader with the Indians named Hughes), and granddaughter of Chief Opechancanough of the Powhatans. According to the Floyd family tradition, "Princess Nicketti" was the source for the name of a descendant Nicketti Buchanan (Floyd) Johnston (1819 - 1908) who was the daughter of John Floyd, Governor of Virginia (1783 - 1837).
Since there is no evidence that either of these purported parents existed, she has been detached from them.
↑ U.S., Sons of the American Revolution Membership Applications, 1889-1970; SAR # 90720. BETTER SOURCE SOUGHT.
↑ Brown, Alexander. The Cabells and their Kin. C. J. Carrier Company, Harrisonburg, VA., 1978, p. 46 or p. 43
(caution-family resource file) The Church of Jesus Christ of Latter-day Saints, "Pedigree Resource File," database, FamilySearch (https://familysearch.org/ark:/61903/2:2:9HX8-X8X : accessed 2017-11-29), entry for Mary Elizabeth Hughes, submitted by bmegginson2732974.
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: