Mary James was christened on 1 Nov 1746 in Paul, Cornwall, England
Her parents were William James and Catherine Beaden
She had 10 siblings:
Elizabeth James
Nicholas James
Grace James
Catherine James
James James
Susanna James
Margaret James
Dorothy James
William James
Richard James
She married Joseph Murrish
Sources
England Births and Christenings, 1538-1975," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:NFBF-G8Q : 6 December 2014), William James in entry for Mary James, 01 Nov 1746; citing Paul, Cornwall, England, reference 51; FHL microfilm 1,596,121.
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DNA Connections
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: