Isham Randolph Jefferson was born about 1791. He was married three times:
Based on Personal Property Taxes recorded in Buckingham County, Virginia, Isham Randolph Jefferson was possibly the second son of Randolph and Anne (Lewis) Jefferson. Called Randolph, Jr. by his family, he appears on most public documents as Isham, Isham R., or I. R. Jefferson. He may have been born as early as 1783/84, very likely before 1788. However, the 1850 and 1860 census records, and his obituaries, indicate his birth was about 1791. In 1834, when Isham Randolph Jefferson married for the third time, it was to a significantly younger woman. It is possible that he adjusted his birth date, lessening the age gap between them.
Isham Randolph Jefferson married for the first time in Fluvanna County, Virginia, on December 20, 1813. His bride was Mary Ann L. Henderson. She was not yet twenty-one years old, and her father, John Henderson, gave his consent for her marriage. Mary Anne was a Lewis cousin, the great-granddaughter of Charles and Mary (Randolph) Lewis.
Within a year of Mary Anne’s death, Isham Randolph Jefferson married another Lewis cousin, Margaret G. Peyton, the daughter of Jane R. Lewis and Craven Peyton, granddaughter of Charles and Mary (Randolph) Lewis. Their marriage bond was recorded in Albemarle County, Virginia on July 2, 1822.
After removing to Todd County, Kentucky with his children from two marriages, Isham Randolph Jefferson married Sarah Ann Mansfield on October 28, 1834.
He died on July 6, 1862 and was buried in Elkton, Todd County. An obituary published in the Nashville Dispatch on August 12, 1862 called him the “nephew and adopted son of Thomas Jefferson,” for which there is no known basis.
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