In 1850 they lived in Chelmsford, Massachusetts. 
New Hampshire [Myrtle??}
E F Josselyn
W A Josselyn
↑ "Massachusetts Births and Christenings, 1639-1915," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:VQ6Z-D9F : 10 February 2018), Charles Josselyn in entry for Edwin Josselyn, 23 Jun 1810; citing PEMBROKE,PLYMOUTH,MASSACHUSETTS, ; FHL microfilm 0873752 IT 1.
↑ "United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MD9B-R3F : 12 April 2016), Edwin Josselyn, Chelmsford, Middlesex, Massachusetts, United States; citing family 69, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
It may be possible to confirm family relationships with Edwin by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Edwin: